8 Common Causes Of Amyloidosis

3. Age-related systemic amyloidosis

This form of amyloidosis, sometimes also referred to as senile amyloidosis is most prominent in older men. The exact reason why cases with older women aren’t as common remains unclear at the moment. This form of amyloidosis occurs when there’s a buildup of TTR in the heart and other surrounding tissues within the body.

A theory proposed by some doctors as to why this form of amyloidosis is more prominent in older men rather than older women is that the higher testosterone levels increase the rate at which TTR builds up in the body, though studies attempting to confirm this theory are at an early stage and thus are unable to make a conclusive report at this time. It’s worth noting that TTR could build up in other tissues of your body without ever touching the hear and still pose a threat to you.


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